Nanomol Pharmaceutical Innovations (NPI):
Your partner in drug discovery and development

Consultation

Consultation in biophysical characterization of HTS and H2L compounds. Site planning/setup of biophysical analytical platforms.

Service

Setup and execution of supportive/confirmatory biophysics experiments for HTS hit confirmation and H2L profiling. Access to high field/high sensitivity NMR instruments.

FBLD

Planning and execution of Fragment Based Lead Discovery (FBLD) projects.

Maintenance

Maintenance, experimental setup and troubleshooting of NMR instrumentation.

Isotopically labeled proteins

By collaboration with South Bay Bio (https://www.south-bay-bio.com/), we can offer labeled and differentially labeled proteins for NMR and MS analysis. For a nice example, see: https://www.nature.com/articles/nature24006

Concepts for integrated biophysics applications in drug discovery:
fast track from binder to structure

Analytical Services:

  • Overnight small molecule characterization starting at 500MHz and up to 700MHz and cryo-probe sensitivity.

  • Assignment and shift mapping of 13C/15N labeled proteins and 19F/31P natural abundance spectra.