Welcome to Nanomol Pharmaceutical Innovations (NPI)
Consultation
Consultation on HTS and H2L compound characterization and data interpretation.
Site planning/setup of biophysical analytical platforms: NMR, MS, SPR, DSF, MST, DLS.
Service
Setup and execution of supportive/confirmatory biophysics experiments for HTS hit confirmation and H2L profiling.
Access to high field/high sensitivity NMR
FBLD
Planning and execution of Fragment Based Lead Discovery projects.
Maintenance
Maintenance and troubleshooting of instrumentation, in particular NMR.
New Products
New Products
Isotopically labeled proteins
By collaboration with South Bay Bio (https://www.south-bay-bio.com/), we can offer labeled and differentially labeled proteins for NMR and MS analysis. For a nice example, see: https://www.nature.com/articles/nature24006
Concepts for Integrated Biophysics Applications in Drug Discovery
Expert Guidance in Fragment Based Lead Identification
Analytical Services:
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Overnight small molecule characterization starting at 500MHz and up to 700MHz and cryo-probe sensitivity.
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Assignment and shift mapping of 13C/15N labeled proteins and 19F/31P natural abundance spectra.